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Synthesis and biological evaluation of some 2-substituted benzimidazoles
Journal article

Synthesis and biological evaluation of some 2-substituted benzimidazoles

S K Gupta, M Imran, Z U Rehman and S A Khan
Asian journal of chemistry, Vol.17(4), pp.2741-2747
01/10/2005

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
Some new 2-substituted benzimidazoles were synthesizsed by the condensation of various clinically used NSAID's and antibacterial agents with different substituted o-phenylenediamine dihydro-chlorides in presence of ethylene glycol. The structures of the title compounds were derived from elemental analysis, IR, H-1 NMR and mass spectral data. The anti inflammatory, analgesic, anticonvulsant and antimicrobial activity of these compounds are also reported.

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