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Synthesis and characterization of new acyclic nucleosides analogues derived from 2-phenyl quinoline candidates
Journal article   Peer reviewed

Synthesis and characterization of new acyclic nucleosides analogues derived from 2-phenyl quinoline candidates

N. M. Khalifa, M. A. Al-Omar and A. E. Amr
Russian journal of general chemistry, Vol.86(5), pp.1115-1119
01/05/2016

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
Reaction of 4-substituted quinoline hydrazide with some aldohexoses and aldopentoses gave a series of new N-beta-glycosides. The following cyclization of N-beta-glycosides with acetic anhydride led to O-acetyl-[5-(2-phenylquinolin-4-yl)-1,3,4-oxadiazol-2-yl]-D-glycosides. Structure of the newly synthesized products was elucidated by chemical and spectroscopic methods.

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