Sign in
Synthesis and evaluation of some substituted 2-arylamino coumarinyl thiazoles as potential NSAIDs
Journal article

Synthesis and evaluation of some substituted 2-arylamino coumarinyl thiazoles as potential NSAIDs

K N Venugopala, B S Jayashree and M Attimarad
Asian journal of chemistry, Vol.16(2), pp.872-876
01/04/2004

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
Substituted 2'-arylamino-4'-(3-coumarinyl) thiazoles (5a-j) and 2'-arylamino-4'-(6-bromo-3-coumarinyl) thiazoles (5k-v) were synthesized by the condensation of respective 3-bromoacetyl-coumarins with thiourea and substituted phenylthioureas. Finally the compounds were characterized by spectral data and screened for their analgesic and anti-inflammatory activities. Some of these compounds exhibited promising activity.

Metrics

1 Record Views

Details