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Synthesis and fluorescence of the new environment-sensitive fluorophore 6-chloro-2,3-naphthalimide derivative
Journal article   Peer reviewed

Synthesis and fluorescence of the new environment-sensitive fluorophore 6-chloro-2,3-naphthalimide derivative

Alan R. Katritzky, Sevil Ozcan and Ekaterina Todadze
Organic & biomolecular chemistry, Vol.8(6), pp.1296-1300
21/03/2010
PMID: 20204199

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Convenient and efficient synthesis of a new environmentally sensitive chlorine-substituted 2,3-naphthalimide-based fluorophore is reported. Benzotriazole carboxyl group activation of the 6-chloro-fluorophore enabled quick labeling of free and Fmoc-protected amino acids. The photophysical properties of the compounds obtained include high quantum yields in solvents of different polarity: water, methanol, acetonitrile and hexane.

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