Abstract
Metformin is one of the most effective drugs for the treatment of type II diabetes. Two new mixed ligand complexes of vanadyl(
) and chromium(
) ions with the general formula [VOL
]SO
and [CrL
(Cl)
]Cl, respectively, where L
is the metformin and L
is the glycine amino acid, have been synthesized in MeOH solvent with 1:1:1 stoichiometry and characterized by several spectroscopic techniques. The spectroscopic data suggested that the [VOL
]SO
complex possesses a square pyramidal geometry, where the [CrL
(Cl)
]Cl complex possesses an octahedral geometry. The L
ligand coordinated to the VO(
) and Cr(
) ions via the N atoms of the imino (‒C═NH) groups, where the L
ligand coordinated via the O atom of the carboxylate group (COO) and the N atom of the amino group (NH
). The interaction of ligands L
and L
with the metal ions leads to complexes that have organized nanoscale structures with a main diameter of ∼14 nm for the [CrL
(Cl)
]Cl complex and ∼40 nm for the [VOL
]SO
complex.