Abstract
The room temperature addition of an aqueous solution of chloroplatinic acid hydrate or cadmium nitrate tetrahydrate to a mixture of an aqueous acetonitrile solution of 1,10-phenanthroline ligand (phen) and sodium azide affords new complexes of [Pt(N3)6Na2(phen)6], (1) and [Cd(phen)2(NO3)2], (2). The complexes 1, 2 were structurally characterized by elemental analysis, Fourier-transform infrared (FT-IR), Ultraviolet–visible (UV–vis), and nuclear magnetic resonance (NMR) spectroscopic techniques. The crystal structure of complexes 1, 2 was examined by single crystal X-ray diffraction. The complex 1 consists of two ionic complexes of [Pt(N3)6]2–and [Na(phen)3]+. The coordination geometry of Pt(IV) ion in complex 1 is distorted octahedral through six N atoms of the six terminal azide groups, while the sodium ion bonded to three phen ligand through six nitrogen atoms. In complex 2, phen and nitrate group act as bidentate ligands coordinating to Cd(II) through their nitrogen and oxygen atoms to form eight coordination. The two phen and nitrate ligands are coordinated to the cadmium in a cis geometry to each other. Three-dimensional supramolecular frameworks of complexes 1, 2 are produced by hydrogen bonding and π-π stacking interactions. The complex 1 was tested for cytotoxicity impact on two tumor cell lines: hepatocellular carcinoma HePG-2 and mammary gland breast cancer MCF-7 using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The results indicate that complex 1 has strong activity on the two cancer cell lines HePG-2 and MCF-7. Also, complex 1 was screened for its antioxidant and anti-haemolytic activities. In addition, complex 2 was used as a heterogeneous catalyst for the degradation of Indigo carmine dye (IC) in the presence of H2O2 as oxidant. Additionally, the luminescence spectra of 1,10-phenanthroline ligand and complexes 1,2 were discussed.
The 3D-network structure of complexes [Pt(N3)6Na2(phen)6], (1) and [Cd(phen)2(NO3)2], (2) is developed by extensive H-bonds and π–π stacking interactions. The complex 1 was tested for cytotoxicity impact on two tumor cell lines: HePG-2 and MCF-7. The complex 2 was used as a heterogeneous catalyst for the degradation of Indigo carmine dye. Additionally, the luminescence spectra of 1,10-phenanthroline ligand and the complexes 1,2 were discussed. [Display omitted]
•The complexes [Pt(N3)6Na2(phen)6], (1) and [Cd(phen)2(NO3)2], (2) were obtained.•The structure was characterized by spectroscopic and single crystal X-ray diffraction.•The cytotoxicity of complex 1 on the viability of HePG-2 and MCF-7 cell lines was also examined.•The catalytic behavior of complex 2 was utilized for the degradation of IC dye.•The luminescence spectra of phen and complexes 1,2 were discussed.