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Synthesis and structure of some thienopyrimidine derivatives
Journal article   Peer reviewed

Synthesis and structure of some thienopyrimidine derivatives

Atef A. Hamed, Ibrahim F. Zeid, Hussein H. El-Ganzory and Mohamed T. Abdel Aal
Monatshefte für Chemie, Vol.139(7), pp.809-820
01/07/2008
DOI: https://doi.org/10.1007/s00706-007-0823-y

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
A series of substituted thieno[2,3-d]pyrimidines was synthesized starting from ethyl-2-amino-4-isopropylthiophene-3-carboxlate. Reaction of 2-hydrazino-5-isopropyl-thieno[2,3-d]pyrimidin-4(3H)-one and its 3-methyl analogue with different reagents afforded thieno[2,3-d]triazolo[4,3-a]pyrimidines and thieno[3,2-e]triazolo[4,3-a]pyrimidines, beside open chain derivatives.

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