Abstract
Cobalt-based nanoparticles are promising candidates towards countless biomedical applications due to their unique characteristics. Co
nanoparticles were synthesized by applying the sol-gel technique and finally sintered at various temperatures (700, 800, 900 °C). The crystal size, morphology, purity, and optical properties were determined using a variety of advanced characterization techniques. To investigate photodynamic therapy feasibility by using Co
nanoparticles in the liver cells, in-vitro cancerous liver cells (HepG2 cells) were exposed to light of wavelength 655 nm (red light) for 30 min at 50 mW cm
and in dark as well. After assessment of cell viability analysis, it is concluded that light-induced photodynamic therapy shows significant phototoxic effects based on temperature dependency.