Abstract
A new group of chiral linear 7-methyl-4-oxo-1,8-naphthyridine-3-carboxamides with incorporated peptide linkage have been synthesized via condensation of 1-ethyl-
N
-(1-hydrazinyl-3-methyl-1-oxobutan-2-yl)-7-methyl–4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide with various derivatives of sugar pentose, acetophenones and thiosemicarbazide. Structures of the products were elucidated by spectroscopic methods and chemical analysis. Antimicrobial properties of the synthesized compounds were tested.