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Synthesis, characterization, and evaluation of some novel 4(3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents
Journal article   Peer reviewed

Synthesis, characterization, and evaluation of some novel 4(3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents

Awatef A. Farag, Ebtsam M. Khalifa, Naima A. Sadik, Samir Y. Abbas, Abdullah G. Al-Sehemi and Yousry A. Ammar
Medicinal chemistry research, Vol.22(1), pp.440-452
01/01/2013
DOI: https://doi.org/10.1007/s00044-012-0046-6

Abstract

Chemistry, Medicinal Life Sciences & Biomedicine Pharmacology & Pharmacy Science & Technology
Some of new 3-(4-chlorophenyl or 4-fluorophenyl)-6-iodo-4-oxo-3,4-dihydroquinazoline derivatives having a Schiff bases, oxazolone, imidazolidine, pyrazolidine, pyridine, pyrimidine, and various substituted C-2 have been synthesized. Screening for some selected compounds was carried out for their potential anti-inflammatory and analgesic activity.

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