Abstract
Complexes of sulfadoxine as a pharmaceutical ligand with Ca(II), Mg(II), Zn(II), Fe(III), and VO(II), were synthesized and characterized by microanalysis, conductance, infrared and thermogravimetric (TGA/DTG and DTA) measurements. The ligand can be coordinate as a bidentate feature via (C=N) and (S=O) groups. Sulfadoxine ligand as well as their complexes has been checked against some kinds of bacteria and fungi which gave a significant effect. The kinetic thermodynamic parameters such as: activation of
E
*, Δ
H
*, Δ
S
*, and Δ
G
* were estimated using Coats-Redfern as well as Horowitz-Metzger equations.