Abstract
Platinum(II) complexes, [Pt(PDTC)(H
2O)Cl] and [Pt(PDTC)(DMSO)Cl] (
1) (PDTC = pyrrolidinedithiocarbamate) have been prepared and characterized by IR, NMR and X-ray crystallographic methods. In the crystal structure of
1 the central platinum atom is coordinated to two sulfur atoms of PDTC, one sulfur atom of DMSO and one chloride ion adopting a square planar geometry with the average
cis and
trans bond angles of 90.00° and 171.62° respectively. The
1H and
13C NMR spectral data indicate the coordination of both PDTC and DMSO to platinum(II). The title complex was screened for antimicrobial effects and the results show that it exhibits significant activity against gram-negative bacteria (
E. coli,
P. aeruginosa), while the activities are moderate against molds (
A. niger, P. citrinum) and yeasts (
C. albicans, S. serevisaiae).
Platinum(II) complexes, [Pt(PDTC)(H
2O)Cl] and [Pt(PDTC)(DMSO)Cl] (
1) (PDTC = pyrrolidinedithiocarbamate) have been prepared and characterized by IR, NMR and X-ray crystallographic methods. In the crystal structure of
1 the platinum atom is coordinated to two sulfur atoms of PDTC, one sulfur atom of DMSO and to one chloride ion adopting a square planar geometry. The complex
1 exhibits significant activity against gram-negative bacteria (
E. coli, P. aeruginosa), while the activities are moderate against molds and yeasts.
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► The synthesis and structural characterization of a novel Platinum(II) complex of pyrrolidinedithiocarbamate and DMSO. ► Investigation of antimicrobial activities. ► The significant antibacterial activities of the complex may lead to the development of new antimicrobial agents.