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Synthesis of 2H-benzo[2,3-g]pyridazino-[4,5-d,e]quinolin-3-one derivatives
Journal article   Peer reviewed

Synthesis of 2H-benzo[2,3-g]pyridazino-[4,5-d,e]quinolin-3-one derivatives

L Chaker, F Pautet and H Fillion
Monatshefte für Chemie, Vol.128(6-7), pp.681-685
01/06/1997

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
Condensation-cyclization of hydrazine with 4-methoxycarbonylbenzo [g]quinolinequinone or its corresponding carboxylic acid afforded 7-hydrazino-2H-benzo[2,3-g]pyridazino [4,5-d,e]-quinolin-3-one. Starting with the 9-hydroxy derivative, a similar double condensation of the nucleophile was observed, whereas its 6-hydroxylated regioisomer gave 2H-benzo[2,3-g]pyridazino[3,5-d,e]quinolin-3,7-dione.

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