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Synthesis of 4 H-benzo[ e]-1,2-selanazin-4-one derivatives: a new heterocyclic ring system
Journal article   Peer reviewed

Synthesis of 4 H-benzo[ e]-1,2-selanazin-4-one derivatives: a new heterocyclic ring system

Mouslim Messali, Léon E. Christiaens, Solhe F. Alshahateet and Fethi Kooli
Tetrahedron letters, Vol.48(42), pp.7448-7451
2007
DOI: https://doi.org/10.1016/j.tetlet.2007.08.082

Abstract

Benzoselenazinone Homoebselen Organoselenium Selenoheterocycle
The synthesis of novel selenoheterocyclic analogues of ebselen is described. The synthesis of novel 1,2-benzoselenazin-4-ones which are six-membered homologues of ebselen, is described in order to evaluate their glutathione peroxidase-like activity.

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