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Synthesis of Biodegradable Pyrazole, Pyran, Pyrrole, Pyrimidine and Chromene Derivatives having Medical and Surface Activities
Journal article   Peer reviewed

Synthesis of Biodegradable Pyrazole, Pyran, Pyrrole, Pyrimidine and Chromene Derivatives having Medical and Surface Activities

Refat El-Sayed
Journal of surfactants and detergents, Vol.19(6), pp.1153-1167
11/2016

Abstract

Chemistry Chemistry, Applied Chemistry, Physical Engineering Engineering, Chemical Physical Sciences Science & Technology Technology
In this research, stearic acid and propylene oxide are used to synthesize biodegradable heterocyles (pyrazole, pyran, chromene, and pyrimidine) to improve their solubility and lower their toxicity. The chemical structure of these surfactants was confirmed using IR, 1H, and C-13 NMR spectra. Some of these compounds have higher activity than commercial antibiotics and may be useful in the pharmaceutical industry.

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