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Synthesis of New 3-Phenyl-2-thioquinazoline Derivatives
Journal article

Synthesis of New 3-Phenyl-2-thioquinazoline Derivatives

Omar M. Ali, Farag A. El-Essawy, Wael A. El-Sayed, Eman Roushdy and Adel A-H. Abdel-Rahman
Asian journal of chemistry, Vol.23(7), pp.2915-2918
01/07/2011

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
A new 3-phenyl-2-thioquinazoline derivatives have been synthesized by the reaction of hydrazide 1 with formic acid and diethylmalonate I to give 2 and 3, n spectively. Compound 1 is reacted with sugar to give the sugar hydrazone (4a-c) which is converted to oxadiazole derivatives (5a-c). The final compounds (6a-c) were obtained by reacting the hydrazones 4a-c with acetic anhydride in pyridine.

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