Abstract
Increase the activity of the clioquinol drug in the presence of Th (IV) metal ion by the formation of new complex. The complex was investigated spectroscopically and thermally. The infrared spectral assignments, the Th(IV) ions coordinated to Clioquinol drug through lone pair of electron on nitrogen and phenoxy group is participate in coordination. The activity of new Th(IV) Clioquinol complex are applied against four species Escherichia coli (G -ve), Bacillus subtilis (G +ve), Aspergillus niger and Aspergillus flavus. The resulted data of Th(IV) complex found to has a highly activity against bacteria and fungi. This work is very industrial and biological important. The metal drug complex has significant effect on therapeutic action of the drugs.