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Synthesis of Novel Pyrazole-sucrose Derivatives by 1,3-dipolar Cycloaddition
Journal article   Peer reviewed

Synthesis of Novel Pyrazole-sucrose Derivatives by 1,3-dipolar Cycloaddition

Khaoula Hajlaoui, Ahlem El Guesmi, Naoufel Ben Hamadi and Moncef Msaddek
Journal of heterocyclic chemistry, Vol.55(9), pp.2069-2074
01/09/2018

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
The syntheses of an important class of enantiopure five-membered glyconjucates containing furan unit are described. The regioselective synthesis of a series of sugar-fused pyrazole heterocycles was achieved by the Huisgen cyclization of aryl diazomethanes with propargyl O-glycoside derivatives in good yields. The cycloaddition regioselectivity was confirmed by NMR.

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