Sign in
Synthesis of Pyrazolyl‐Pyrazoles and Pyrazolyl‐[1,2,4]‐Triazolo[3,4‐d][1,5]Benzothiazepines as p53 Activators Using Hydrazonoyl Chlorides
Journal article   Peer reviewed

Synthesis of Pyrazolyl‐Pyrazoles and Pyrazolyl‐[1,2,4]‐Triazolo[3,4‐d][1,5]Benzothiazepines as p53 Activators Using Hydrazonoyl Chlorides

Sobhi M. Gomha, Thoraya A. Farghaly, Abdelwahed R. Sayed and Mohamed M. Abdalla
Journal of heterocyclic chemistry, Vol.53(5), pp.1505-1511
09/2016

Abstract

Di‐pyrazoles, tripyrazoles, and pyrazolyltriazolobenzothiazepines were prepared from α,β‐unsaturated ketones and hydrazonoyl chlorides. The structure of all the newly synthesized compounds was established on the bases of their spectral data and elemental analyses. The activity of all products was examined as p53 ubiquitination which showed promising activities.

Metrics

1 Record Views

Details