Abstract
Diospyrin and its analogues have been known for their antimycobacterial properties. Significant efforts have been made towards the synthesis Of Structural analogues of diospyrin with improved biological activities. We report here the synthesis Of four novel analogues of diospyrin via a Suzuki cross coupling between bromonaphthoquin ones and aryl- or naplithylboronic acids ill the presence of tetrakis(triphenylphosphine)palladium(0) as catalyst, followed by selective demethylation of the intermediates.