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Synthesis of Selenium-Containing Amino Acid Analogues and Their Biological Study
Journal article   Peer reviewed

Synthesis of Selenium-Containing Amino Acid Analogues and Their Biological Study

Sh. H. Abdel-Hafez, H. A. Saad and M. R. E. Aly
Russian journal of bioorganic chemistry, Vol.37(3), pp.261-269
01/05/2011

Abstract

Biochemistry & Molecular Biology Chemistry Chemistry, Organic Life Sciences & Biomedicine Physical Sciences Science & Technology
Synthesis of selenium-containing amino acid analogues is described. These compounds were prepared in a concise and short synthetic route in good yields by nucleophilic substitution reaction of pyridineselenol and quinolineselenol derivatives with N-phthaloylglycyl chloride followed by hydrazinolysis. The newly synthesized compounds were screened against different strains of bacteria and fungi.

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