Abstract
In this paper, two new complexes of selenium caffeine, [Se(Caf)
4
], and zinc α-tocopherol, [Zn(α-Tpl)
2
(NO
3
)
2
], are synthesized. The structures of complexes are characterized by IR, Raman and
1
H NMR spectra, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray powder diffraction (XRD), and thermogravimetric (TG/DTG) analysis. According to conductivity measurements the complexes are non-electrolytes. Spectroscopic studies of Se
0
caffeine complex indicate its monodentate coordination via nitrogen atom N
9
at 1: 4 molar ratio metal-to-ligand. In [Zn(α-Tpl)
2
(NO
3
)
2
], α-Tpl chelate is coordinated as a monodentate ligand via oxygen atom of the hydroxyl group with 1: 2 metal-to-ligand molar ratio. The percentage scavenging activity of hydroxyl radical (IC
50
= 0.21 and 0.32 µg/mL), DPPH (0.17 and 0.30 µg/mL) and superoxide anion scavenging activity (0.18 and 0.32 µg/mL) indicate that selenocaffeine complex is of higher potential antioxidant activity than zinc(II) α-tocopherol complex.