Abstract
A novel β -enaminonitrile of 1-(6-p-tolyl-pyridazin-3-yl)-pyrazole derivative
2
was formed using (6-p-tolyl-pyridazin-3-yl)-hydrazine (
1
) and 2-ethoxymethylenemalononitrile. The β-enaminonitrile derivative
2
was in turn used as a precursor for the preparation of pyrazoles (
4
,
6
), pyrazolo[3, 4-d]-pyrimidines (
3
,
7-12
) and pyrazolo[4, 3-e][1,2,4]triazolo[4,3-c]pyrimidine (
13
). Also, N- and S-acyclic nucleosides
14
and
15
were prepared. Some of the prepared products showed potent antimicrobial activity.