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Synthesis of Thiazolidine and Thiophene Derivatives for Evaluation as Anticancer Agents
Journal article   Peer reviewed

Synthesis of Thiazolidine and Thiophene Derivatives for Evaluation as Anticancer Agents

M. S. A. El-Gaby, Z. H. Ismail, S. M. Abdel-Gawad, H. M. Aly and M. M. Ghorab
Phosphorus, sulfur, and silicon and the related elements, Vol.184(10), pp.2645-2654
13/10/2009
DOI: https://doi.org/10.1080/10426500802561096

Abstract

1,2,5-Thiadiazole thiazolidine and thiophene derivatives
The non-isolated adducts (3a,b) were used as key intermediates to synthesize some novel thiazolidine and thiophene derivatives. Compound (4) exhibited a remarkable antitumor activity against EAC cells compared with the Doxorubicin as a positive control.

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