Sign in
Back
Synthesis of alpha, beta and gamma-carbolines via Pd-mediated C-sp(2)-H/N-H activation
Journal article   Peer reviewed

Synthesis of alpha, beta and gamma-carbolines via Pd-mediated C-sp(2)-H/N-H activation

Shubhendu Dhara, Raju Singha, Atiur Ahmed, Haridas Mandal, Munmun Ghosh, Yasin Nuree and Jayanta K. Ray
RSC advances, Vol.4(85), pp.45163-45167
01/01/2014
DOI: https://doi.org/10.1039/c4ra08457h

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
An efficient method for the synthesis of halo-carbolines has been developed via Pd-catalysed formation of C-N bonds through C-sp(2)-H/N-H activation of 4-methyl-N-[2-(pyridine-3-yl)phenyl] benzene-sulfonamide derivatives. Pd(OAc)(2) in the presence of Cu(OAc)(2) as oxidant afforded halo-carbolines in good to excellent yields with tolerance to a variety of substituents.

Metrics

1 Record Views

Details