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Synthesis of bis-exocyclic conjugated diene containing 1,2,3,4-tetrahydroquinoline derivatives via palladium-catalyzed intramolecular Heck cyclization
Journal article   Peer reviewed

Synthesis of bis-exocyclic conjugated diene containing 1,2,3,4-tetrahydroquinoline derivatives via palladium-catalyzed intramolecular Heck cyclization

Munmun Ghosh, Shubhendu Dhara, Yasin Nuree and Jayanta K. Ray
RSC advances, Vol.4(78), pp.41561-41564
01/01/2014
DOI: https://doi.org/10.1039/c4ra05900j

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
An efficient method has been developed for the synthesis of bis-exocyclic conjugated diene containing 1,2,3,4-tetrahydroquinoline derivatives via palladium-catalyzed intramolecular Heck cyclization of (2bromo-allyl)-(2-phenylethynyl-phenyl)-amines. The reaction followed 6-exo-dig cyclization to yield the desired products in moderate to good yields.

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