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Synthesis of highly functionalized 2-thiaspiro[4.5]deca-6,8-dienes via atom efficient tandem Michael addition/Thorpe-Ziegler cyclization
Journal article   Peer reviewed

Synthesis of highly functionalized 2-thiaspiro[4.5]deca-6,8-dienes via atom efficient tandem Michael addition/Thorpe-Ziegler cyclization

Mani Anusha Rani, Sundaravel Vivek Kumar, Somi Santharam Roja, Abdulrahman I. Almansour, Raju Suresh Kumar, S. Athimoolam and Raju Ranjith Kumar
RSC advances, Vol.6(46), pp.40585-40592
01/01/2016
DOI: https://doi.org/10.1039/c6ra05572a

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
The two-component reaction of 2,4-bis((Z)-arylidene)dihydrothiophen-3(2H)-ones and 2-(1-arylethylidene)malononitriles proceeded through a tandem chemoselective Michael addition-tautomerization-Thorpe-Ziegler cyclization sequence of reactions in a single step affording novel 2-thiaspiro[4.5]deca-6,8-dienes in quantitative yields.

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