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Synthesis of nanoporous calcium carbonate spheres using double hydrophilic block copolymer poly(acrylic acid-b-N-isopropylacrylamide)
Journal article   Peer reviewed

Synthesis of nanoporous calcium carbonate spheres using double hydrophilic block copolymer poly(acrylic acid-b-N-isopropylacrylamide)

Sudhina Guragain, Nagy L. Torad, Yousef Gamaan Alghamdi, Abdulmohsen Ali Alshehri, Jeonghun Kim, Bishnu Prasad Bastakoti and Yusuke Yamauchi
Materials letters, Vol.230, pp.143-147
01/11/2018
DOI: https://doi.org/10.1016/j.matlet.2018.07.060

Abstract

Materials Science Materials Science, Multidisciplinary Physical Sciences Physics Physics, Applied Science & Technology Technology
We report self-assembly of double hydrophilic block copolymer poly(acrylic acid-b-N-isopropylacrylamide) in aqueous solution. Self-assembly of calcium ions chelated complex micelles upon mineralization reaction forms calcium carbonate (CaCO3) sphere. High porosity on CaCO3 spheres can accommodate a large amount of anticancer drug (doxorubicin) and achieve sustainable drug release. (C) 2018 Elsevier B.V. All rights reserved.

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