Abstract
Dopamine conjugated protoporphyrin, PPD, was prepared by the coupling reaction of protoporphyrin IX and dopamine in the presence of dicyclohexylcarbodiimide (DCC) and N-hydroxysuccinimide (NHS) in DMF. The crude product was washed with ethanol–cyclohexane (1:1) mixture to remove dicyclohexylurea (DCU). Previously prepared Fe
3O
4 nanoparticles were coated with PPD (sub-7
nm monosize) by sonication in the methanol. The porphyrin coated Fe
3O
4 nanoparticles, PPDNP were separated by permanent magnet. The microstructure and magnetic properties of magnetic nanoparticles were characterized by XRD, TEM, FT-IR, and VSM. It is found that the nanoparticles have high crystallinity with distinct lattices and the magnetic measurements reveal their well-defined superparamagnetic behavior at room temperature.