Abstract
Methyl 3-bromo-3-benzoylpropionate on treatment with substituted phenylthioureas yielded substituted 2-phenylamino-4-phenylthiazole-5-acetates (5a-k), which on hydrolysis furnished thiazole-5-acetic acids (6a-i). The structures of the compounds have been established on the basis of their elemental analysis and spectral data. The anti inflammatory, analgesic and antioxidant activities of some of the compounds have also been evaluated.