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Synthesis of some new biologically active coumarin derivatives
Journal article   Peer reviewed

Synthesis of some new biologically active coumarin derivatives

N Hamdi, C Lidrissi, M Saoud, A R Nievas and H Zarrouk
Khimiia geterotsiklicheskikh soedineniĭ, (3), pp.361-366
01/03/2006

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
The reaction of 4-hydroxycoumarin in toluene with a variety of aromatic binucleophilic compounds has been studied. 3-(Dimethylaminomethylene)chromane-2,4-dione was used as a key intermediate for the preparation of bis[N-(4-oxocoumarinylmethylene)]-1,4-diamines. Alternative synthetic procedures and antibacterial activity data of some of the new compounds are given.

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