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Synthesis of some new pyrazole and indazole derivatives as potential antiinflammatory agents
Journal article   Peer reviewed

Synthesis of some new pyrazole and indazole derivatives as potential antiinflammatory agents

Mohd Amir, H. K. Agarwal, S. A. Javed and H. Kumar
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, Vol.16(2), pp.175-178
01/10/2006

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
Some new 3-chloro-4-substituted pyrazolyl-1-benzenesulphonamides (3a-c), N-[4-(substituted pyrazolyi)-3-chlorophenyl] methane sulphonamides (6a-c) and 1-substituted benzoyl-6-acetoxy-3-methyl-1H-indazoles (9a-g) have been synthesized. Some of the newly synthesized compounds have been screened for their antiinflammatory and ulcerogenic activities. The compounds were found to possess significant antiinflammatory activity with reduced ulcerogenic effect.

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