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Synthesis of some novel S-alkylated and S-glycosylated hydantoin derivatives containing pyrene moiety
Journal article   Peer reviewed

Synthesis of some novel S-alkylated and S-glycosylated hydantoin derivatives containing pyrene moiety

N. M. Khalifa, E. S. Nossier, M. A. Al-Omar and A. E. Amr
Russian journal of general chemistry, Vol.86(4), pp.919-923
01/04/2016

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
3-Aryl-5-[(Z)-pyrenylmethylene]-2-alkylthiohydantoins and 3-Aryl-5-[(Z)-pyrenylmethylene]-2-(D-glycosyl)-2-thiohydantoins functionalized with different aromatic and glycoside substituents have been synthesized by the reaction of (Z)-3-(4-methoxyphenyl)-5-[(pyren-8-yl)methylene]-2-thiohydantoin with alkyl halides, cyclic and acyclic nucleosides via various routes with moderate to good yields and characterized by H-1, C-13 NMR and mass spectra and elemental analysis.

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