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Synthesis of some substituted 6,7-dihydro-4-methoxy-7-methyl-7-substituted-5-oxo-5H-furo[3,2-g]chromene-9-sulfonate derivatives as potent antihypertensive alpha-blocking and antiarrythmic agents
Journal article   Peer reviewed

Synthesis of some substituted 6,7-dihydro-4-methoxy-7-methyl-7-substituted-5-oxo-5H-furo[3,2-g]chromene-9-sulfonate derivatives as potent antihypertensive alpha-blocking and antiarrythmic agents

A. E. Amr, M. M. Abdalla, S. A. Essaouy, M. M. H. Areef, M. H. Elgamal, T. A. Nassear and A. E. Haschich
Russian journal of general chemistry, Vol.87(8), pp.1826-1833
01/08/2017
DOI: https://doi.org/10.1134/S1070363217080308

Abstract

Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
A number of substituted 4-methoxy-7-methyl-6-(substituted methyl)-5-oxo-5H-furo[3,2-g]-chromene-9-sulfonates 3a-3f and 4a-4c were synthesized. Treatment of visnagin-9-sulphonyl esters by secondary amines gave the substituted 6,7-dihydro-4-methoxy-7-methyl-7-substituted-5-oxo-5H-furo[3,2-g]-chromene-9-sulfonates 5a-5f and 6a-6c. Some of synthesized compounds were tested as potential alpha-blocking and antiarrythmic agents.

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