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Synthesis of some thiopyrimidine and thiazolopyrimidines starting from 2,6-dibenzylidene-3-methylcyclohexanone and its antimicrobial activities
Journal article   Open access  Peer reviewed

Synthesis of some thiopyrimidine and thiazolopyrimidines starting from 2,6-dibenzylidene-3-methylcyclohexanone and its antimicrobial activities

Usama W. Hawas, Mohamed A. Al-Omar, Abdel Galil E. Amr and Abu El-Ftouh G. Hammam
Arabian journal of chemistry, Vol.5(4), pp.509-515
10/2012

Abstract

2,6-Dibenzylidene-3-methyl-cyclohexanone Antimicrobial agents Thiazolopyridine Thiopyrimidine
A series of novel N-substituted arylidene, pyrazole, thioxopyrimidine and thiazolopyrimidine derivatives 2–7 were synthesized by initial reactions of 2-methyl-cyclohexanone with aromatic aldehydes to give 2,6-dibenzylidene-3-methylcyclohexanone 2. Some of the synthesized compounds were tested as antimicrobial agents. The detailed synthesis, spectroscopic data, and antimicrobial activities of the synthesized compounds were reported.
url
https://doi.org/10.1016/j.arabjc.2010.09.019View
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