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Synthesis of spiro-linked quinolinone-pyrrolidine/pyrrolo[1,2-c] thiazole-oxindoleiacenaphthalene hybrids via multi-component [3+2] cycloaddition
Journal article   Peer reviewed

Synthesis of spiro-linked quinolinone-pyrrolidine/pyrrolo[1,2-c] thiazole-oxindoleiacenaphthalene hybrids via multi-component [3+2] cycloaddition

Remani Vasudevan Sumesh, Adaikalam Shylaja, Raju Ranjith Kumar, Abdulrahman I. Almansour and Raju Suresh Kumar
Tetrahedron letters, Vol.59(46), pp.4086-4089
14/11/2018
DOI: https://doi.org/10.1016/j.tetlet.2018.10.002

Abstract

Chemistry Chemistry, Organic Physical Sciences Science & Technology
The syntheses of novel spiro-linked quinolinone-pyrrolidine/pyrrolo[1,2-c]thiazole-oxindole/acenaphthalene hybrid heterocycles have been achieved through a one-pot three-component [3 + 2] cycloaddition strategy. The reaction proceeded stereoselectively affording these structurally intriguing multi-spiro compounds in excellent yields. (C) 2018 Elsevier Ltd. All rights reserved.

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