Abstract
(22E)-
N
'-(4-Methoxybenzylidene)-2-[3-cyano-7,8-dihydro-4-(5-methylfuran-2-yl)-2-oxo-2
H
-pyrano[ 4,3-
b
]pyridin-1(5
H
)-yl]acetohydrazide (2) was synthesized from 2-[3-cyano-7,8-dihydro-4-(5-methylfuran- 2-yl)-2-oxo-2H-pyrano[4,3-
b
]pyridin-1(5
H
)-yl]acetohydrazide (1) as starting material with 4-methoxybenzaldehyde. The product
2
2 was evaluated for antimicrobial activity against gram positive and gram negative bacteria in comparison with Vebromycine as the standard antibiotics. Compound
2
, C
24
H
22
N
4
O
5
, crystallized as triclinic,
P
-1,
a
= 8.3496(5) Å,
b
= 10.9465(9) Å,
c
= 12.1495(9) Å,
a
= 74.694(4)°, β = 84.793(3)°, γ = 84.495 (3)°,
V
= 1063.64(13) Å
3
,
Z
= 2.