Abstract
Reactions of K-2[PdCl4] with heterocyclic thiones in molar ratios of 1:2 and 1:4 in water-methanol medium yielded the palladium(II) complexes with the general formula of either [Pd(L)Cl-2], [Pd(L)(2)]Cl-2 or [Pd(L)(4)]Cl-2 where L = Imidazolidine-2-thione (Imt), 2-Mercaptopyridine (Mpy), 2-Mercaptopyrimidine (Mpm), 6-Mercaptopurine (6-Mp) and Thionicotinamide (Tna). The complexes were characterized by elemental analysis and spectroscopic (IR, H-1 and C-13 NMR) methods. An upfield shift in the >C=S resonance of thiones in C-13 NMR and downfield shift in N-H or aromatic proton resonances in H-1 NMR are consistent with the sulfur coordination to palladium(II). The complexes were screened for antibacterial activity, and the results showed that the complexes exhibited moderate activities as compared to that of a standard drug.