Abstract
New five ciprofloxacin (CIP) complexes of dioxouranium(II), oxozirconium(II), zirconium(IV), oxovanadium(II) and vanadium(IV) in the proportion 1:2 have been prepared using CIP as a drug chelate with UO
(NO
. 6H
O, ZrOCl
.
O, ZrCl
, VOSO
. xH
O and V
respectively. The CIP complexes have been characterized based on the elemental analysis, molar conductance, magnetic, (FTIR &
HNMR) spectral and thermal studies. The molar conductance studies of the synthesized complexes in DMSO solvent with concentration of 10
M indicate their non-electrolytic properties. At room temperature, the magnetic moment measurements revealed a diamagnetic behavior for all CIP prepared complexes. The different formulas of the new complexes can be represented as [UO
(CIP)
(NO
] (
), [VO(CIP)
(SO
)(H
O)] (
), [V
(O)(O
(CIP)
] (
), [Zr(O)(CIP)
(Cl)
] (
), and [Zr(CIP)
(Cl)
] (
). The thermal analysis data of the complexes indicates the absence of coordinated water molecules except for vanadyl(II) complex (
). The CIP chelate is a uni-dentate ligand coordinated to the mentioned metal ion through terminal piperazinyl nitrogen. The transmission electron microscopy (TEM) investigation confirms the nano-structured form of the complexes.