Abstract
The solid-state structure of 3a,8a-dihydroxy-2-thioxo-1,3,3a,8a-tetrahydroindeno[1,2-d]imidazol-8(2H)-one (3) was determined using X-ray single crystal technique. Its non-covalent interactions were analyzed carefully in terms of crystal engineering and supramolecular chemistry. Multiple sulfur-hydrogen and oxygen-hydrogen interactions are present in the structure, most commonly involving bifurcated H S H motifs which resulted in formation interesting centrosymmetric dimmers. This compound demonstrated comparable antimicrobial activity to that of clinically used antimicrobial agents against selected microorganisms. (C) 2011 Elsevier B.V. All rights reserved.