Abstract
Biologically active flavone derivatives with. antibacterial potentials were synthesized via Claisen-Schmidt condensation of ketones with different aldehydes with good yields. The structures were established by, different spectroscopic techniques like H-1 NMR, C-13 NMR, IR and elemental analysis. The findings showed that some of the substituted flavones possess higher antibacterial potentials than simple flavones as regards their minimum inhibitory concentration (MIC) and are potential candidates for the treatment of a wide range of infectious diseases.