THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

Stephen PH Alexander; Arthur Christopoulos; Anthony P Davenport; Eamonn Kelly; Alistair Mathie; John A Peters; Emma L Veale; Jane F Armstrong; Elena Faccenda; Simon D Harding; Adam J Pawson; Christopher Southan; Jamie A Davies; Maria Pia Abbracchio; Wayne Alexander; Khaled Al-hosaini; Magnus Bäck; Nicholas M. Barnes; Ross Bathgate; Jean‐Martin Beaulieu; Kenneth E. Bernstein; Bernhard Bettler; Nigel J.M. Birdsall; Victoria Blaho; Francois Boulay; Corinne Bousquet; Hans Bräuner-Osborne; Geoffrey Burnstock; Girolamo Caló; Justo P. Castaño; Kevin J. Catt; Stefania Ceruti; Paul Chazot; Nan Chiang; Bice Chini; Jerold Chun; Antonia Cianciulli; Olivier Civelli; Lucie H. Clapp; Réjean Couture; Zsolt Csaba; Claes Dahlgren; Gordon Dent; Khuraijam Dhanachandra Singh; Steven D. Douglas; Pascal Dournaud; Satoru Eguchi; Emanuel Escher; Edward J. Filardo; Tung Fong; Marta Fumagalli; Raul R Gainetdinov; Marc de Gasparo; Craig Gerard; Marvin Gershengorn; Fernand Gobeil; Theodore L. Goodfriend; Cyril Goudet; Karen J. Gregory; Andrew L. Gundlach; Jörg Hamann; Julien Hanson; Richard L. Hauger; Debbie L. Hay; Akos Heinemann; Morley D. Hollenberg; Nicholas D. Holliday; Mastgugu Horiuchi; Daniel Hoyer; László Hunyady; Ahsan Husain; Adriaan P. IJzerman; Tadashi Inagami; Kenneth A. Jacobson; Robert T. Jensen; Ralf Jockers; Deepa Jonnalagadda; Sadashiva Karnik; Klemens Kaupmann; Jacqueline Kemp; Charles Kennedy; Yasuyuki Kihara; Takio Kitazawa; Pawel Kozielewicz; Hans‐Jürgen Kreienkamp; Jyrki P. Kukkonen; Tobias Langenhan; Katie Leach; Davide Lecca; John D. Lee; Susan E. Leeman; Jérôme Leprince; Xaria X. Li; Tom Lloyd Williams; Stephen J. Lolait; Amelie Lupp; Robyn Macrae; Janet Maguire; Jean Mazella; Craig A. McArdle; Shlomo Melmed; Martin C. Michel; Laurence J. Miller; Vincenzo Mitolo; Bernard Mouillac; Christa E. Müller; Philip Murphy; Jean‐Louis Nahon; Tony Ngo; Xavier Norel; Duuamene Nyimanu; Anne‐Marie O’Carroll; Stefan Offermanns; Maria Antonietta Panaro; Marc Parmentier; Roger G. Pertwee; Jean‐Philippe Pin; Eric R. Prossnitz; Mark Quinn; Rithwik Ramachandran; Manisha Ray; Rainer K. Reinscheid; Philippe Rondard; G. Enrico Rovati; Chiara Ruzza; Gareth J. Sanger; Torsten Schöneberg; Gunnar Schulte; Stefan Schulz; Deborah L. Segaloff; Charles N. Serhan; Leigh A. Stoddart; Yukihiko Sugimoto; Roger Summers; Valerie P. Tan; David Thal; Walter (Wally) Thomas; Pieter B. M. W. M. Timmermans; Kalyan Tirupula; Giovanni Tulipano; Hamiyet Unal; Thomas Unger; Celine Valant; Patrick Vanderheyden; David Vaudry; Hubert Vaudry; Jean‐Pierre Vilardaga; Christopher S. Walker; Ji Ming Wang; Donald T. Ward; Hans‐Jürgen Wester; Gary B Willars; Trent M. Woodruff; Chengcan Yao; Richard D. Ye; Sahlgrenska akademin

doi:10.1111/bph.15538

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THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

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THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

Stephen PH Alexander, Arthur Christopoulos, Anthony P Davenport, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, …

British journal of pharmacology, Vol.178(S1), pp.S27-S156

10/2021

DOI: https://doi.org/10.1111/bph.15538

PMID: 34529832

Abstract

The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15538. G protein‐coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

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Title: THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors
Creators - without role: Stephen PH Alexander - University of Nottingham
Arthur Christopoulos - Monash University
Anthony P Davenport - University of Cambridge
Eamonn Kelly - University of Bristol
Alistair Mathie - University of Suffolk
John A Peters - Ninewells Hospital
Emma L Veale - Medway School of Pharmacy
Jane F Armstrong - University of Edinburgh
Elena Faccenda - University of Edinburgh
Simon D Harding - University of Edinburgh
Adam J Pawson - University of Edinburgh
Christopher Southan - University of Edinburgh
Jamie A Davies - University of Edinburgh
Maria Pia Abbracchio - University of Milan
Wayne Alexander - Emory University
Khaled Al-hosaini - King Saud University
Magnus Bäck - Karolinska University Hospital
Nicholas M. Barnes - University of Birmingham
Ross Bathgate - Florey Institute of Neuroscience and Mental Health
Jean‐Martin Beaulieu - University of Toronto
Kenneth E. Bernstein - Cedars-Sinai Medical Center
Bernhard Bettler - University of Basel
Nigel J.M. Birdsall - The Francis Crick Institute
Victoria Blaho - Discovery Institute
Francois Boulay - Université Grenoble Alpes
Corinne Bousquet - Inserm
Hans Bräuner-Osborne - University of Copenhagen
Geoffrey Burnstock - UCL Australia
Girolamo Caló - University of Padua
Justo P. Castaño - University of Córdoba
Kevin J. Catt - National Institute of Health
Stefania Ceruti - University of Milan
Paul Chazot - Durham University
Nan Chiang - Harvard University
Bice Chini - University of Milano-Bicocca
Jerold Chun - University of California, San Diego
Antonia Cianciulli - University of Bari Aldo Moro
Olivier Civelli - University of California, Irvine
Lucie H. Clapp - University College London
Réjean Couture - Université de Montréal
Zsolt Csaba - Inserm
Claes Dahlgren - University of Gothenburg
Gordon Dent - Keele University
Khuraijam Dhanachandra Singh - Cleveland Clinic Lerner College of Medicine
Steven D. Douglas - California University of Pennsylvania
Pascal Dournaud - Inserm
Satoru Eguchi - Temple University
Emanuel Escher - Université de Sherbrooke
Edward J. Filardo - University of Iowa
Tung Fong - LabCorp
Marta Fumagalli - University of Milan
Raul R Gainetdinov - St Petersburg University
Marc de Gasparo - MG Consulting Co
Craig Gerard - Harvard University
Marvin Gershengorn - National Institute of Health
Fernand Gobeil - Université de Sherbrooke
Theodore L. Goodfriend - University of Wisconsin–Madison
Cyril Goudet - French National Centre for Scientific Research
Karen J. Gregory - Monash University
Andrew L. Gundlach - Florey Institute of Neuroscience and Mental Health
Jörg Hamann - Amsterdam University
Julien Hanson - University of Liège
Richard L. Hauger - University of California, San Diego
Debbie L. Hay - University of Otago
Akos Heinemann - Medical University of Graz
Morley D. Hollenberg - University of Calgary
Nicholas D. Holliday - University of Nottingham
Mastgugu Horiuchi - Ehime University
Daniel Hoyer - University of Melbourne
László Hunyady - Semmelweis University
Ahsan Husain - Emory University
Adriaan P. IJzerman - Leiden University
Tadashi Inagami - Vanderbilt University
Kenneth A. Jacobson - National Institute of Health
Robert T. Jensen - National Institute of Health
Ralf Jockers - Inserm
Deepa Jonnalagadda - Discovery Institute
Sadashiva Karnik - Lerner Research Institute
Klemens Kaupmann - Novartis
Jacqueline Kemp - Cleveland Clinic Lerner College of Medicine
Charles Kennedy - University of Strathclyde
Yasuyuki Kihara - Discovery Institute
Takio Kitazawa - Rakuno Gakuen University
Pawel Kozielewicz - Karolinska Institutet
Hans‐Jürgen Kreienkamp - Universität Hamburg
Jyrki P. Kukkonen - University of Helsinki
Tobias Langenhan - Leipzig University
Katie Leach - Monash University
Davide Lecca - University of Milan
John D. Lee - University of Queensland
Susan E. Leeman - Boston University
Jérôme Leprince - Université de Rouen Normandie
Xaria X. Li - University of Queensland
Tom Lloyd Williams - University of Cambridge
Stephen J. Lolait - University of Bristol
Amelie Lupp - Friedrich Schiller University Jena
Robyn Macrae - University of Cambridge
Janet Maguire - University of Cambridge
Jean Mazella - Centre de Gestion Scientifique
Craig A. McArdle - University of Bristol
Shlomo Melmed - Cedars‐Sinai Medical Center
Martin C. Michel - Johannes Gutenberg University Mainz
Laurence J. Miller - Mayo Foundation for Medical Education and Research
Vincenzo Mitolo - University of Bari Aldo Moro
Bernard Mouillac - French National Centre for Scientific Research
Christa E. Müller - University of Bonn
Philip Murphy - Edge Hill University
Jean‐Louis Nahon - French National Centre for Scientific Research(CNRS)
Tony Ngo - Sanford Burnham Prebys Medical Discovery Institute
Xavier Norel - French Institute of Health and Medical Research(INSERM)
Duuamene Nyimanu - University of Cambridge
Anne‐Marie O’Carroll - University of Bristol
Stefan Offermanns - Max Planck Institute for Heart and Lung Research
Maria Antonietta Panaro - University of Bari Aldo Moro
Marc Parmentier - Free University of Brussels
Roger G. Pertwee - University of Aberdeen
Jean‐Philippe Pin - University of Montpellier
Eric R. Prossnitz - University of New Mexico
Mark Quinn - Montana State University
Rithwik Ramachandran - University of Calgary
Manisha Ray - Sanford Burnham Prebys Medical Discovery Institute
Rainer K. Reinscheid - Friedrich Schiller University Jena
Philippe Rondard - University of Montpellier
G. Enrico Rovati - University of Milan
Chiara Ruzza - University of Ferrara
Gareth J. Sanger - Queen Mary University of London
Torsten Schöneberg - University of Leipzig
Gunnar Schulte - Karolinska Institutet
Stefan Schulz - Friedrich Schiller University Jena
Deborah L. Segaloff - University of Iowa
Charles N. Serhan - Harvard University
Leigh A. Stoddart - University of Nottingham
Yukihiko Sugimoto - Kumamoto University
Roger Summers - Monash University
Valerie P. Tan - University of California, San Diego
David Thal - Monash University
Walter (Wally) Thomas - University of Queensland
Pieter B. M. W. M. Timmermans - Kosan Biosciences
Kalyan Tirupula - Cleveland Clinic
Giovanni Tulipano - University of Brescia
Hamiyet Unal - Cleveland Clinic
Thomas Unger - Maastricht University
Celine Valant - Monash University
Patrick Vanderheyden - Free University of Brussels
David Vaudry - Université de Rouen Normandie
Hubert Vaudry - Université de Rouen Normandie
Jean‐Pierre Vilardaga - University of Pittsburgh
Christopher S. Walker - University of Auckland
Ji Ming Wang - National Institute of Health
Donald T. Ward - University of Manchester
Hans‐Jürgen Wester - Technical University of Munich
Gary B Willars - University of Leicester
Trent M. Woodruff - University of Queensland
Chengcan Yao - University of Edinburgh
Richard D. Ye - University of Illinois Urbana-Champaign
Sahlgrenska akademin
Publication Details: British journal of pharmacology, Vol.178(S1), pp.S27-S156
Number of pages: 130
Identifiers: 9950096708331
Academic Unit: King Saud University
Language: English
Resource Type: Journal article