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TICAGRELOR POTENTIATES NEUTROPHIL PHAGOCYTOSIS VIA INHIBITION OF ADENOSINE REUPTAKE BY ERYTHROCYTES
Journal article   Open access  Peer reviewed

TICAGRELOR POTENTIATES NEUTROPHIL PHAGOCYTOSIS VIA INHIBITION OF ADENOSINE REUPTAKE BY ERYTHROCYTES

Mark Thomas, Khalaf Alsharif, Lynne Prince, Victoria Ridger, Heather Judge, David Dockrell, Ian Sabroe and Robert Storey
Journal of the American College of Cardiology, Vol.65(10), pp.A259-A259
17/03/2015
DOI: https://doi.org/10.1016/S0735-1097(15)60259-5

Abstract

Adenosine Fish Streptococcus infections
Results: In the presence of erythrocytes, a low concentration of adenosine (10 nM) significantly increased neutrophil phagocytosis compared to control when ticagrelor was present (37.6±6.6 vs. 28.0±6.6; p=0.028) but had no effect in the absence of ticagrelor (25.3±5.6 vs. 25.1±7.5; p>0.05).
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https://doi.org/10.1016/S0735-1097(15)60259-5View
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