Abstract
This study aimed to evaluate the toxic influences of cyfluthrin pesticide and ameliorated their effects by Solenostemma argel as antioxidant agents on blood glucose, liver glycogen, lactate dehydrogenase (LDH), pyruvate kinase (PK), and hexokinase (HK) activities as well as lactate and pyruvate contents of liver, brain and kidneys. The S. argel potency as antioxidant was determined by DPPH and ABTS in aqueous and methanolic extracts. Results showed that pesticide ingestion increased blood glucose but decreased liver glycogen. Activity of LDH was inhibited but HK and PK- activities were stimulated also lactate and pyruvate content were reduced in all tissues. Treatments reduced these disturbances of the cyfluthrin effects on above glycolytic enzymes and metabolites in the all organs tissue. It can be concluded that S. argel methanolic extract treatments as antioxidant agent improved the disturbed carbohydrate metabolism induced by cyfluthrin than aqueous extract.