Abstract
Upper limb dysfunction is a. significant cause of disability after stroke. Previous studies have shown that the application of low frequency focused ultrasound as a brain stimulation technique modulates the function of the primary somato sensory motor cortex by enhancing sensory discriminative tasks, and application on the primary motor cortex provided cortical excitability. Ultrasound has only recently emerged as a non-invasive human neuromodulation technique for its distinct advantages over other electrotherapcutic techniques such as providing superior specificity and penetrability, eventually enhancing cortical plasticity stroke-aifected hemisphere to provide post-stroke regains in upper limb functions.