Targeting LIN28: a new hope in prostate cancer theranostics

Garima Shrivastava; Alaa A. A. Aljabali; Seyed Hossein Shahcheraghi; Marzieh Lotfi; Madhur D. Shastri; Shakti D. Shukla; Dinesh K. Chellappan; Niraj Kumar Jha; Krishnan Anand; Harish Dureja; Ritesh M. Pabari; Vijay Mishra; Abdulmajeed G. Almutary; Abdullah M. Alnuqaydan; Nitin Charbe; Parteek Prasher; Poonam Negi; Rohit Goyal; Kamal Dua; Gaurav Gupta; Angel Serrano-Aroca; Bojlul Bahar; Debmalya Barh; Pritam Kumar Panda; Kazuo Takayama; Kenneth Lundstorm; Paul McCarron; Hamid Bakshi; Murtaza M. Tambuwala

doi:10.2217/fon-2021-0247

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Targeting LIN28: a new hope in prostate cancer theranostics

Journal article

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Targeting LIN28: a new hope in prostate cancer theranostics

Garima Shrivastava, Alaa A. A. Aljabali, Seyed Hossein Shahcheraghi, Marzieh Lotfi, Madhur D. Shastri, Shakti D. Shukla, Dinesh K. Chellappan, Niraj Kumar Jha, Krishnan Anand, Harish Dureja, …

Future oncology (London, England), Vol.17(29), pp.3873-3880

01/10/2021

DOI: https://doi.org/10.2217/fon-2021-0247

PMID: 34263659

Abstract

Life Sciences & Biomedicine

Oncology

Science & Technology

The mortality and morbidity rates for prostate cancer have recently increased to alarming levels, rising higher than lung cancer. Due to a lack of drug targets and molecular probes, existing theranostic techniques are limited. Human LIN28A and its paralog LIN28B overexpression are associated with a number of tumors resulting in a remarkable increase in cancer aggression and poor prognoses. The current review aims to highlight recent work identifying the key roles of LIN28A and LIN28B in prostate cancer, and to instigate further preclinical and clinical research in this important area.

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Title: Targeting LIN28: a new hope in prostate cancer theranostics
Creators - without role: Garima Shrivastava - Indian Institute of Technology Delhi
Alaa A. A. Aljabali - Yarmouk University
Seyed Hossein Shahcheraghi - Shahid Sadoughi University of Medical Sciences and Health Services
Marzieh Lotfi - Shahid Sadoughi University of Medical Sciences and Health Services
Madhur D. Shastri - University of Tasmania
Shakti D. Shukla - University of Newcastle Australia
Dinesh K. Chellappan - Supreme Council Of Health
Niraj Kumar Jha - Sharda University
Krishnan Anand - University of the Free State
Harish Dureja - GITAM University
Ritesh M. Pabari - College Station Medical Center
Vijay Mishra - Lovely Professional University
Abdulmajeed G. Almutary - Qassim University
Abdullah M. Alnuqaydan - Qassim University
Nitin Charbe - Pontificia Universidad Católica de Chile
Parteek Prasher - University of Petroleum and Energy Studies
Poonam Negi - Shoolini University
Rohit Goyal - Shoolini University
Kamal Dua - International Medical University
Gaurav Gupta - Gyan Vihar University
Angel Serrano-Aroca - Valencia Catholic University Saint Vincent Martyr
Bojlul Bahar - University of Central Lancashire
Debmalya Barh - Universidade Federal de Minas Gerais
Pritam Kumar Panda - Uppsala University
Kazuo Takayama - Kyoto University
Kenneth Lundstorm - PanTherapeutics, Lutry CH1095, Switzerland.
Paul McCarron - University of Ulster
Hamid Bakshi - University of Ulster
Murtaza M. Tambuwala - University of Ulster
Publication Details: Future oncology (London, England), Vol.17(29), pp.3873-3880
Publisher: Future Medicine Ltd
Number of pages: 8
Identifiers: 9928452908331
Academic Unit: Qassim University
Language: English
Resource Type: Journal article