Abstract
Introduction. - DRESS syndrome is a rare disorder initiated by an immunological reaction to drugs. The diagnosis is difficult due to multiple clinical presentations that can mimic viral infections or autoimmun diseases. We report a case of DRESS syndrome in a 45-year-old woman, induced by teicoplanin treatment for sternoclavicular arthritis. The diagnosis of DRESS syndrome was retained due to patient presenting a feverish peak at 39 degrees C, a maculopapular rash, cervical adenopathy, a facial edema and subiterus. Blood samples showed total white blood cell count of 19,500 with a mononucleosis syndrome, an hepatic cytolysis, a creatinine level at 159 mu mol/L. The evolution was favorable after stopping antibiotic and initiating corticosteroid therapy 1 mg/kg/d. (C) 2015 Elsevier Masson SAS. All rights reserved.