Abstract
[ReX(CO)(3)(L-k(2)N(1),N-2)] (L = 4'-(4-phenyl morpholine)-2,2':6',2''-terpyridine, X = Br- (1), N-3(-) (2), and triazolate (3)) complexes were synthesized, and characterized using different spectroscopic and analytical tools including single-crystal X-ray diffraction analysis of 2. The 1,3-dipolar cycloaddition reaction between 2, and 4,4,4-trifluoro-2-butynoic acid ethyl ester afforded triazolate 3. Although, the crystal structure of 2 showed that the azide ligand is terminally coordinated to Re(CO)3+ unit, the F-19 and H-1 NMR analyses of 3 provided conversant evidences that the kinetically formed N(1) triazolate bound isomer favoured the isomerization to N(2) form. The photophysical properties of 1-3 were investigated by recording the absorption spectra of the compounds in solvents of different polarities. Complexes 1 and 3 were screened for their potential antimicrobial activities. The protein binding affinity of 1, and 3 towards hen white egg lysozyme revealed that the bromide complex exchanges Br- with that protein, while the triazolate analogue sticked around. (C) 2020 Elsevier Ltd. All rights reserved.