Abstract
Objective: To identify whether or not there was a correlation between low serum 25(OH)D and hypothyroidism
Design: Retrospective study
Setting: King Abdulaziz University Hospital, from June 2014 to June 2016
Subjects: One thousand and forty-two patients suffering from hypothyroidism were enrolled in this retrospective study and serum 25(OH)D levels were measured in all patients. We divided them into two groups; the first included 373 patients with post radioactive Iodine (RAI) ablation hypothyroidism and the second group included 669 patients with Hashimoto's hypothyroidism.
Main outcome measures: Vitamin D states in hypothyroid patients
Results: In the first group, 335 patients (90%) were afflicted with vitamin D deficiency and 636 patients (95%) from the second group were afflicted with vitamin D deficiency. Furthermore, it was also found that levels of serum 25(OH)D were lower in the Hashimoto's group at 13.7 ng/mL in comparison with the post-RAI group at 15.6 ng/mL. There was no significant correlation between the serum thyroid-stimulating hormone (TSH) and the 25(OH)D parameter in patients with post-RAI hypothyroidism as per the Pearson scale reading (r = -0.004, p = 0.94). Similarly, the patients afflicted with Hashimoto's disease had no significant correlation between their serum 25(OH)D and TSH levels since the Pearson scale read r = -0.04, p = 0.3.
Conclusion: Low serum 25(OH)D levels was found to be common amongst the patients affected with hypothyroidism.