Abstract
Migraine is a common disabling primary headache disorder. It affects 6% of men and 18% of women worldwide and 12.1% in Saudi Arabia. The lack of many nutrients like vitamin B-12 and magnesium is associated with migraine. Migraine may be socicated with cardiovascular risk factors such as a high level of cholesterol. Ninety-one Saudi female patients with a mean age of 32.91 +/- 1.187 and fifty-four healthy Saudi females (control) with a mean age of 30.00 +/- 1.32 years participated in this study. Serum lipid profile, vitamin B-12, and magnesium levels were measured in both patients and controls. The results showed a significant increase in serum cholesterol and low-density lipoprotein (LDL), and lower levels of high-density lipoprotein (HDL) for migraine patients. However, no significant difference has been observed in triglyceride serum levels. No significant differences were found in vitamin B-12 and magnesium (Mg) serum levels between the two groups (migraine patients and control). In conclusion, lipid profile was shown to be associated with Saudi female patients with migraine. Vitamin B-12 serum levels and mg serum levels were not significantly correlated in migraine patientsand controls.